Establishment of cell lines that exhibit pluripotency from miniature swine periodontal ligaments.

Periodontal ligament stem cell-mediated treatment for periodontitis in miniature swine.

Periodontitis is a periodontal tissue infectious disease and the most common cause for tooth loss in adults. It has been linked to many systemic disorders, such as coronary artery disease, stroke, and diabetes. At present, there is no ideal therapeutic approach to cure periodontitis and achieve optimal periodontal tissue regeneration. In this study, we explored the potential of using autologous...

Effects of Mouse Strain on Establishment of Embryonic Stem Cell Lines

Purpose: Embryonic stem (ES) cells are derived from the inner cell mass of blastocysts with self-renewal and pluripotency characteristics. These cells have potential for studies of in vitro differentiation, gene function, etc. This study was, therefore, initiated to establish new ES lines and evaluate the effects of strain on ES cell production. Materials and Methods: 3-5 day blastocysts were ...

A Mathematical Approach for Describing Time-Dependent Poisson’s Ratios of Periodontal Ligaments

Periodontal ligament is a thin layer of soft tissue that connects root of a tooth to the surrounding alveolar bone. These ligaments play an important role in initiating tooth movement when loads are applied to teeth with orthodontic appliances. The majority of such soft tissues exhibit as viscoelastic bodies or have a time-dependent behavior. Due to the viscoelastic behavior of the periodontal ...

A Nano-indentation Identification Technique for Viscoelastic Constitutive Characteristics of Periodontal Ligaments

Introduction: Nano-indentation has recently been employed as a powerful tool for determining the mechanical properties of biological tissues on nano and micro scales. A majority of soft biological tissues such as ligaments and tendons exhibit viscoelastic or time-dependent behaviors. The constitutive characterization of soft tissues is among very important subjects in clinical medicine and espe...

Establishment of Transplantable Porcine Tumor Cell Lines Derived from MHC Inbred Miniature Swine Running Title: Transplantable Porcine Tumor Cell Lines